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ChEMBL ligand: CHEMBL236822 (SQ-24798) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Carboxypeptidase B in Pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4065] [UniProtKB: P09955] | ||||||||
ChEMBL | Inhibition of porcine pancreatic carboxypeptidase B | B | 9.38 | pKi | 0.42 | nM | Ki | J Med Chem (2007) 50: 6095-6103 [PMID:17990866] |
ChEMBL | Inhibition of porcine pancreatic carboxypeptidase B | B | 8 | pIC50 | 10 | nM | IC50 | Bioorg Med Chem Lett (2007) 17: 1349-1354 [PMID:17189688] |
Carboxypeptidase B2 (plasma)/Carboxypeptidase B2 isoform A in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3419] [GtoPdb: 1594] [UniProtKB: Q96IY4] | ||||||||
ChEMBL | Inhibition of human TAFIa | B | 8.4 | pKi | 4 | nM | Ki | J Med Chem (2007) 50: 6095-6103 [PMID:17990866] |
GtoPdb | - | - | 8.4 | pKi | 4 | nM | Ki | J Med Chem (2007) 50: 6095-103 [PMID:17990866] |
ChEMBL | Inhibition of human activated thrombin activatable fibrinolysis inhibitor | B | 8.1 | pIC50 | 8 | nM | IC50 | Bioorg Med Chem Lett (2007) 17: 1349-1354 [PMID:17189688] |
Carboxypeptidase N, polypeptide 1/Carboxypeptidase N, catalytic subunit in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4713] [GtoPdb: 1597] [UniProtKB: P15169] | ||||||||
ChEMBL | Inhibition of human plasma carboxypeptidase N | B | 8.7 | pKi | 2 | nM | Ki | J Med Chem (2007) 50: 6095-6103 [PMID:17990866] |
GtoPdb | - | - | 8.7 | pKi | 2 | nM | Ki | J Med Chem (2007) 50: 6095-103 [PMID:17990866] |
ChEMBL | Inhibition of human carboxypeptidase N | B | 8.7 | pIC50 | 2 | nM | IC50 | Bioorg Med Chem Lett (2007) 17: 1349-1354 [PMID:17189688] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]