Gene and Protein Information
class C G protein-coupled receptor
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	7	839	1p36.13	TAS1R2	taste 1 receptor member 2
Mouse	7	843	4 70.82 cM	Tas1r2	taste receptor, type 1, member 2

Previous and Unofficial Names

GPR71 | T1R2 | TR2 | G protein-coupled receptor 71 | taste receptor, type 1, member 2 | taste receptor

Database Links
Specialist databases
GPCRdb	ts1r2_human (Hs), ts1r2_mouse (Mm)
Other databases
Alphafold	Q8TE23 (Hs), Q925I4 (Mm)
ChEMBL Target	CHEMBL1613741 (Hs)
Ensembl Gene	ENSG00000179002 (Hs), ENSMUSG00000028738 (Mm)
Entrez Gene	80834 (Hs), 83770 (Mm)
Human Protein Atlas	ENSG00000179002 (Hs)
KEGG Gene	hsa:80834 (Hs), mmu:83770 (Mm)
OMIM	606226 (Hs)
Pharos	Q8TE23 (Hs)
RefSeq Nucleotide	NM_152232 (Hs), NM_031873 (Mm)
RefSeq Protein	NP_689418 (Hs), NP_114079 (Mm)
UniProtKB	Q8TE23 (Hs), Q925I4 (Mm)
Wikipedia	TAS1R2 (Hs)

Download all structure-activity data for this target as a CSV file

Agonists
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference aspartame Hs Agonist - - 1 ⤷ [1] Description: G-protein coupling determined using a cell-based calcium assay in cells co-expressing the G protein Gα15-Gust44 plus TAS1R2 and TAS1R3

General Comments
TAS1R2 is a putative sweet taste receptor