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Adipo2 receptor

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Target id: 650

Nomenclature: Adipo2 receptor

Family: Adiponectin receptors

Contents:

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 7 386 12p13.33 ADIPOR2 adiponectin receptor 2
Mouse 7 386 6 56.78 cM Adipor2 adiponectin receptor 2
Rat - - 4q42 Adipor2 adiponectin receptor 2
Previous and Unofficial Names Click here for help
ACDCR2 | PAQR2 | adiponectin receptor 2 | progestin and adipoQ receptor family member II
Database Links Click here for help
Alphafold Q86V24 (Hs), Q8BQS5 (Mm)
ChEMBL Target CHEMBL3392947 (Hs)
Ensembl Gene ENSG00000006831 (Hs), ENSMUSG00000030168 (Mm), ENSRNOG00000007990 (Rn)
Human Protein Atlas ENSG00000006831 (Hs)
OMIM 607946 (Hs)
Pharos Q86V24 (Hs)
UniProtKB Q86V24 (Hs), Q8BQS5 (Mm)
Wikipedia ADIPOR2 (Hs)
Selected 3D Structures Click here for help
Image of receptor 3D structure from RCSB PDB
Description:  Crystal structure of the human adiponectin receptor 2
PDB Id:  3WXW
Resolution:  2.4Å
Species:  Human
References:  1
Natural/Endogenous Ligands Click here for help
adiponectin {Sp: Human}
globular adiponectin {Sp: Human}
Rank order of potency (Human)
globular adiponectin (ADIPOQ, Q15848) = adiponectin (ADIPOQ, Q15848)
Immuno Process Associations
Immuno Process:  Cytokine production & signalling

References

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1. Tanabe H, Fujii Y, Okada-Iwabu M, Iwabu M, Nakamura Y, Hosaka T, Motoyama K, Ikeda M, Wakiyama M, Terada T et al.. (2015) Crystal structures of the human adiponectin receptors. Nature, 520 (7547): 312-6. [PMID:25855295]

How to cite this page

Adiponectin receptors: Adipo2 receptor. Last modified on 27/04/2015. Accessed on 24/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetomalariapharmacology.org/GRAC/ObjectDisplayForward?objectId=650.