Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	287	19q13.42	LAIR1	leukocyte associated immunoglobulin like receptor 1
Mouse	1	263	7 2.31 cM	Lair1	leukocyte-associated Ig-like receptor 1
Rat	1	263	1q21	Lair1	leukocyte-associated immunoglobulin-like receptor 1
Gene and Protein Information Comments
Multiple transcript variants encoding different isoforms have been found for the human and mouse genes. We provide the RefSeqs and gene/protein information for isoform 1 (Hs) and isoform a (Mm)..

Previous and Unofficial Names

Lair-1 | leukocyte-associated Ig-like receptor 1 | leukocyte-associated immunoglobulin-like receptor 1

Database Links
Alphafold	Q6GTX8 (Hs), Q8BG84 (Mm), P0C1X9 (Rn)
Ensembl Gene	ENSG00000167613 (Hs), ENSMUSG00000055541 (Mm), ENSRNOG00000027733 (Rn)
Entrez Gene	3903 (Hs), 52855 (Mm), 574531 (Rn)
Human Protein Atlas	ENSG00000167613 (Hs)
KEGG Gene	hsa:3903 (Hs), mmu:52855 (Mm), rno:574531 (Rn)
OMIM	602992 (Hs)
Pharos	Q6GTX8 (Hs)
RefSeq Nucleotide	NM_002287 (Hs), NM_001113474 (Mm), NM_001029928 (Rn)
RefSeq Protein	NP_002278 (Hs), NP_001106945 (Mm), NP_001025099 (Rn)
UniProtKB	Q6GTX8 (Hs), Q8BG84 (Mm), P0C1X9 (Rn)
Wikipedia	LAIR1 (Hs)

Immunopharmacology Comments

LAIR1 has been identified as a potential molecular receptor for Plasmodium falciparum-coded proteins that are expressed by infected host erythrocytes. Interaction of these parasite RIFIN proteins (encoded by rif genes) and inhibitory leucocyte receptors such as LAIR1 may mediate parasite-driven evasion of the host's immune system [1].

Immuno Process Associations

Immuno Process:  Inflammation

Immuno Process:  T cell (activation)

Immuno Process:  B cell (activation)

Immuno Process:  Immune regulation

Immuno Process:  Cellular signalling

General Comments
LAIR1 (CD305) is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells.