Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	404	19p13.2	CD209	CD209 molecule
Gene and Protein Information Comments
A number of splice variants, encoding different protein isoforms of human CD209 have been identified. The mouse has five CD209 homologs and there are no rat homologs.

Previous and Unofficial Names

CDSIGN | CLEC4L

Database Links
Alphafold	Q9NNX6 (Hs)
CATH/Gene3D	3.10.100.10
ChEMBL Target	CHEMBL1795114 (Hs)
Ensembl Gene	ENSG00000090659 (Hs)
Entrez Gene	30835 (Hs)
Human Protein Atlas	ENSG00000090659 (Hs)
KEGG Gene	hsa:30835 (Hs)
OMIM	604672 (Hs)
Pharos	Q9NNX6 (Hs)
RefSeq Nucleotide	NM_021155 (Hs)
RefSeq Protein	NP_066978 (Hs)
UniProtKB	Q9NNX6 (Hs)
Wikipedia	CD209 (Hs)

Immunopharmacology Comments

DC-SIGN is a pathogen-recognition receptor involved in initiating the primary immune response to various viral and bacterial pathogens, as well as antigen presentation and initiation of the adaptive immune response.

Cell Type Associations

Immuno Cell Type:  Macrophages & monocytes

Immuno Process Associations

Immuno Process:  Inflammation

Immuno Process:  Antigen presentation

Immuno Process:  T cell (activation)

Immuno Process:  Immune regulation

Immuno Process:  Chemotaxis & migration

Immuno Process:  Cellular signalling

Immuno Process:  Barrier integrity

Immuno Process:  B cell (activation)

General Comments
DC-SIGN (CD209) is a pathogen-recognition receptor expressed on the surface of immature dendritic cells.