Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	321	16p13.3	TPSG1	tryptase gamma 1
Mouse	1	311	17 12.53 cM	Tpsg1	tryptase gamma 1
Rat	-	311	10q12	Tpsg1	tryptase gamma 1

Previous and Unofficial Names

tryptase gamma I | Prss31 | Tmt | transmembrane tryptase | tryptase gamma II

Database Links
Specialist databases
MEROPS	S01.028 (Hs)
Other databases
Alphafold	Q9NRR2 (Hs), Q9QUL7 (Mm)
BRENDA	3.4.21.-
ChEMBL Target	CHEMBL4955 (Hs)
Ensembl Gene	ENSG00000116176 (Hs), ENSMUSG00000033200 (Mm), ENSRNOG00000018701 (Rn)
Entrez Gene	25823 (Hs), 26945 (Mm), 302990 (Rn)
Human Protein Atlas	ENSG00000116176 (Hs)
KEGG Enzyme	3.4.21.-
KEGG Gene	hsa:25823 (Hs), mmu:26945 (Mm), rno:302990 (Rn)
OMIM	609341 (Hs)
Pharos	Q9NRR2 (Hs)
RefSeq Nucleotide	NM_012467 (Hs), NM_012034 (Mm), NM_175593 (Rn)
RefSeq Protein	NP_036599 (Hs), NP_036164 (Mm), NP_783183 (Rn)
UniProtKB	Q9NRR2 (Hs), Q9QUL7 (Mm)
Wikipedia	TPSG1 (Hs)

Enzyme Reaction
EC Number: 3.4.21.-

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference WX-UK1 ? Inhibition 5.2 pKi 1 ⤷ pKi 5.2 (Ki 6.3x10-6 M) [1]