Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	1243	17q21.2	WNK4	WNK lysine deficient protein kinase 4
Mouse	-	1222	11 D	Wnk4	WNK lysine deficient protein kinase 4
Rat	-	1222	10q31	Wnk4	WNK lysine deficient protein kinase 4

Previous and Unofficial Names

PRKWNK4

Database Links
Alphafold	Q96J92 (Hs), Q80UE6 (Mm), Q7TPK6 (Rn)
BRENDA	2.7.11.1
ChEMBL Target	CHEMBL1795196 (Hs)
Ensembl Gene	ENSG00000126562 (Hs), ENSMUSG00000035112 (Mm), ENSRNOG00000020441 (Rn)
Entrez Gene	65266 (Hs), 69847 (Mm), 287715 (Rn)
Human Protein Atlas	ENSG00000126562 (Hs)
KEGG Enzyme	2.7.11.1
KEGG Gene	hsa:65266 (Hs), mmu:69847 (Mm), rno:287715 (Rn)
OMIM	601844 (Hs)
Orphanet	ORPHA120534 (Hs)
Pharos	Q96J92 (Hs)
RefSeq Nucleotide	NM_032387 (Hs), NM_175638 (Mm), NM_175579 (Rn)
RefSeq Protein	NP_115763 (Hs), NP_783569 (Mm), NP_783169 (Rn)
UniProtKB	Q96J92 (Hs), Q80UE6 (Mm), Q7TPK6 (Rn)
Wikipedia	WNK4 (Hs)

Enzyme Reaction
EC Number: 2.7.11.1

Clinically-Relevant Mutations and Pathophysiology
Disease:  Pseudohypoaldosteronism, type IIB; PHA2B Synonyms: Pseudohypoaldosteronism [Disease Ontology: DOID:4479] Pseudohypoaldosteronism type 2B [Orphanet: ORPHA88939] Disease Ontology: DOID:4479 OMIM: 614491 Orphanet: ORPHA88939