Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	571	1p34.1	TESK2	testis associated actin remodelling kinase 2
Mouse	-	570	4 D1	Tesk2	testis-specific kinase 2
Rat	-	570	5q35	Tesk2	testis associated actin remodelling kinase 2

Previous and Unofficial Names

dual specificity testis-specific protein kinase 2 | testicular protein kinase 2

Database Links
Alphafold	Q96S53 (Hs), Q8VCT9 (Mm), Q924U5 (Rn)
BRENDA	2.7.12.1
ChEMBL Target	CHEMBL2069163 (Hs)
Ensembl Gene	ENSG00000070759 (Hs), ENSMUSG00000033985 (Mm), ENSRNOG00000017282 (Rn)
Entrez Gene	10420 (Hs), 230661 (Mm), 170908 (Rn)
Human Protein Atlas	ENSG00000070759 (Hs)
KEGG Enzyme	2.7.12.1
KEGG Gene	hsa:10420 (Hs), mmu:230661 (Mm), rno:170908 (Rn)
OMIM	604746 (Hs)
Pharos	Q96S53 (Hs)
RefSeq Nucleotide	NM_007170 (Hs), NM_146151 (Mm), NM_133396 (Rn)
RefSeq Protein	NP_009101 (Hs), NP_666263 (Mm), NP_596887 (Rn)
UniProtKB	Q96S53 (Hs), Q8VCT9 (Mm), Q924U5 (Rn)
Wikipedia	TESK2 (Hs)

Enzyme Reaction
EC Number: 2.7.12.1

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference compound 31 [PMID: 22902653] Hs Inhibition 6.6 pIC50 1 ⤷ pIC50 6.6 (IC50 2.52x10-7 M) [1] compound 30 [PMID: 22902653] Hs Inhibition 6.4 pIC50 1 ⤷ pIC50 6.4 (IC50 4.15x10-7 M) [1] compound 35 [PMID: 22902653] Hs Inhibition <4.5 pIC50 1 ⤷ pIC50 <4.5 (IC50 >3x10-5 M) [1]