Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	655	11p15.4	NLRP10	NLR family pyrin domain containing 10
Mouse	-	673	7 E3	Nlrp10	NLR family, pyrin domain containing 10
Rat	-	-	1q33	Nlrp10	NLR family, pyrin domain containing 10

Previous and Unofficial Names

Pynod | NALP10 | NOD8 | PAN5 | NACHT, leucine rich repeat and PYD containing 10 | NLR family, pyrin domain containing 10 | CLR11.1 | NLR family

Database Links
Alphafold	Q86W26 (Hs), Q8CCN1 (Mm)
Ensembl Gene	ENSG00000182261 (Hs), ENSMUSG00000049709 (Mm), ENSRNOG00000015082 (Rn)
Entrez Gene	338322 (Hs), 244202 (Mm), 293426 (Rn)
Human Protein Atlas	ENSG00000182261 (Hs)
KEGG Gene	hsa:338322 (Hs), mmu:244202 (Mm), rno:293426 (Rn)
OMIM	609662 (Hs)
Pharos	Q86W26 (Hs)
UniProtKB	Q86W26 (Hs), Q8CCN1 (Mm)
Wikipedia	NLRP10 (Hs)

Immunopharmacology Comments

NLRP10 is an intracellular pattern recognition receptor (PRR) that has apoptotic and anti-inflammatory functions [1]. Unlike other other NOD-like receptors, NLRP10 is missing the characteristic leucine-rich repeat domain.

Immuno Process Associations

Immuno Process:  Inflammation

Immuno Process:  T cell (activation)

Immuno Process:  B cell (activation)

Immuno Process:  Immune regulation

Immuno Process:  Cytokine production & signalling

Physiological Functions Comments

Involved in antigen-presenting cell migration, T-Cell priming and NOD1 signalling enhancement.