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Interleukin 17 receptor A

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Target id: 1738

Nomenclature: Interleukin 17 receptor A

Family: IL-17 receptor family

Quaternary Structure: Complexes
Interleukin-17 receptor
Interleukin-25 receptor
Interleukin-17C receptor
Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 866 22q11.1 IL17RA interleukin 17 receptor A
Mouse 1 864 6 56.95 cM Il17ra interleukin 17 receptor A
Rat - - Il17ra interleukin 17 receptor A
Previous and Unofficial Names Click here for help
CD217 | VDw217 | Interleukin-17 α receptor
Database Links Click here for help
Alphafold
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
Pharos
UniProtKB
Wikipedia

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Antibodies
Key to terms and symbols Click column headers to sort
Antibody Sp. Action Value Parameter Reference
brodalumab Peptide Approved drug Primary target of this compound Immunopharmacology Ligand Hs Binding 9.2 pKd 1
pKd 9.2 (Kd 6.9x10-10 M) [1]
Immunopharmacology Comments
This protein is a common subunit shared by the heterodimeric receptors for interleukins 17 (A, B , C and F) and 25.
Immuno Process Associations
Immuno Process:  Cytokine production & signalling
Immuno Process:  Inflammation
Immuno Process:  Immune regulation
Immuno Process:  Chemotaxis & migration

References

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1. Tocker J, Mehlin C, Lim AC. (2010) Neutralizing determinants of IL-17 Receptor A and antibodies that bind thereto. Patent number: US7767206. Assignee: Amgen Inc.. Priority date: 02/10/2006. Publication date: 03/08/2010.

How to cite this page

IL-17 receptor family: Interleukin 17 receptor A. Last modified on 07/04/2017. Accessed on 19/06/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetomalariapharmacology.org/GRAC/ObjectDisplayForward?objectId=1738.