Quaternary Structure: Complexes

Interleukin-18 receptor

Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	541	2q12.1	IL18R1	interleukin 18 receptor 1
Mouse	1	537	1 B	Il18r1	interleukin 18 receptor 1
Rat	-	-		Il18r1	interleukin 18 receptor 1

Previous and Unofficial Names

CD218a | Il18ralpha | IL1RRP | interleukin 18 receptor 1

Database Links
Alphafold	Q13478 (Hs), Q61098 (Mm)
CATH/Gene3D	2.60.40.10, 3.40.50.10140
ChEMBL Target	CHEMBL4804253 (Hs)
Ensembl Gene	ENSG00000115604 (Hs), ENSMUSG00000026070 (Mm), ENSRNOG00000015027 (Rn)
Entrez Gene	8809 (Hs), 16182 (Mm), 301365 (Rn)
Human Protein Atlas	ENSG00000115604 (Hs)
KEGG Gene	hsa:8809 (Hs), mmu:16182 (Mm), rno:301365 (Rn)
OMIM	604494 (Hs)
Pharos	Q13478 (Hs)
UniProtKB	Q13478 (Hs), Q61098 (Mm)
Wikipedia	IL18R1 (Hs)

Immunopharmacology Comments

Interleukin-18 1 protein (IL18R1) is the ligand binding subunit of the functional IL-18 receptor heterodimer.

Immuno Process Associations

Immuno Process:  Immune regulation

Immuno Process:  Inflammation

Immuno Process:  T cell (activation)

Immuno Process:  B cell (activation)

Immuno Process:  Immune system development

Immuno Process:  Cytokine production & signalling

Immuno Process:  Cellular signalling