Quaternary Structure: Complexes

Interleukin-10 receptor

Interleukin-22α1/10β heteromer

Interferon-λ receptor 1

Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	325	21q22.11	IL10RB	interleukin 10 receptor subunit beta
Mouse	1	349	16 52.87 cM	Il10rb	interleukin 10 receptor, beta
Rat	-	-		Il10rb	interleukin 10 receptor subunit beta

Previous and Unofficial Names

CRF2-4 | CRFB4 | IL-10R2 | Il10rb | Interleukin-10 β | interleukin 10 receptor, beta | interleukin 10 receptor

Database Links
Alphafold	Q08334 (Hs), Q61190 (Mm)
CATH/Gene3D	2.60.40.10
ChEMBL Target	CHEMBL3831284 (Hs), CHEMBL4804254 (Hs), CHEMBL4804251 (Hs)
Ensembl Gene	ENSG00000243646 (Hs), ENSMUSG00000022969 (Mm), ENSRNOG00000028638 (Rn)
Entrez Gene	3588 (Hs), 16155 (Mm), 304091 (Rn)
Human Protein Atlas	ENSG00000243646 (Hs)
KEGG Gene	hsa:3588 (Hs), mmu:16155 (Mm), rno:304091 (Rn)
OMIM	123889 (Hs)
Pharos	Q08334 (Hs)
UniProtKB	Q08334 (Hs), Q61190 (Mm)
Wikipedia	IL10RB (Hs)

Immunopharmacology Comments

Interleukin 10 receptor, β subunit is a component of the functional receptor heterodimers for interleukins 10 and 22 and for interferons λ1, λ2 and λ3.

Immuno Process Associations

Immuno Process:  Inflammation

Immuno Process:  Cytokine production & signalling