Quaternary Structure: Complexes

Interferon-γ receptor

Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	337	21q22.11	IFNGR2	interferon gamma receptor 2
Mouse	-	-		Ifngr2	interferon gamma receptor 2
Rat	-	-		Ifngr2	interferon gamma receptor 2

Previous and Unofficial Names

AF-1 | IFNGT1 | interferon gamma receptor 2 | Ifgr2 | interferon gamma receptor 2 (interferon gamma transducer 1)

Database Links
Alphafold	P38484 (Hs)
CATH/Gene3D	2.60.40.10
ChEMBL Target	CHEMBL2364171 (Hs)
DrugBank Target	P38484 (Hs)
Ensembl Gene	ENSG00000159128 (Hs), ENSMUSG00000022965 (Mm), ENSRNOG00000002032 (Rn)
Entrez Gene	3460 (Hs), 15980 (Mm), 360697 (Rn)
Human Protein Atlas	ENSG00000159128 (Hs)
KEGG Gene	hsa:3460 (Hs), mmu:15980 (Mm), rno:360697 (Rn)
OMIM	147569 (Hs)
Pharos	P38484 (Hs)
UniProtKB	P38484 (Hs)
Wikipedia	IFNGR2 (Hs)

Immunopharmacology Comments

A subunit of the functional receptor for interferon γ.

Immuno Process Associations

Immuno Process:  Inflammation GO Annotations:  Associated to 3 GO processes GO:0004906 type II interferon receptor activity TAS GO:0060333 type II interferon-mediated signaling pathway IC click arrow to show/hide IEA associations GO:0001774 microglial cell activation IEA

Immuno Process:  Cytokine production & signalling GO Annotations:  Associated to 4 GO processes GO:0004896 cytokine receptor activity IBA GO:0004906 type II interferon receptor activity TAS GO:0019221 cytokine-mediated signaling pathway IBA GO:0060333 type II interferon-mediated signaling pathway IC

Immuno Process:  Cellular signalling GO Annotations:  Associated to 1 GO processes, IEA only click arrow to show/hide IEA associations GO:0001774 microglial cell activation IEA