Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	266	4q34.1	HPGD	15-hydroxyprostaglandin dehydrogenase
Mouse	-	269	8 B2	Hpgd	hydroxyprostaglandin dehydrogenase 15 (NAD)
Rat	-	266	16p11	Hpgd	15-hydroxyprostaglandin dehydrogenase

Previous and Unofficial Names

15-hydroxyprostaglandin dehydrogenase (NAD)  | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 15-PGDH | PGDH | prostaglandin dehydrogenase 1 | hydroxyprostaglandin dehydrogenase 15-(NAD) | hydroxyprostaglandin dehydrogenase 15 (NAD)

Database Links
Alphafold	P15428 (Hs), Q8VCC1 (Mm), O08699 (Rn)
BRENDA	1.1.1.141
ChEMBL Target	CHEMBL1293255 (Hs)
Ensembl Gene	ENSG00000164120 (Hs), ENSMUSG00000031613 (Mm), ENSRNOG00000010610 (Rn)
Entrez Gene	3248 (Hs), 15446 (Mm), 79242 (Rn)
Human Protein Atlas	ENSG00000164120 (Hs)
KEGG Enzyme	1.1.1.141
KEGG Gene	hsa:3248 (Hs), mmu:15446 (Mm), rno:79242 (Rn)
OMIM	601688 (Hs)
Pharos	P15428 (Hs)
UniProtKB	P15428 (Hs), Q8VCC1 (Mm), O08699 (Rn)
Wikipedia	HPGD (Hs)

Enzyme Reaction
EC Number: 1.1.1.141 Description Reaction Reference 15-hydroxyprostaglandins => 15-ketoprostaglandins LXA4 => 15-keto-lipoxin A4 1

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Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference compound 3 [PMID: 21650226] Hs Inhibition 8.1 pIC50 2 ⤷ pIC50 8.1 (IC50 8x10-9 M) [2]