apelin receptor early endogenous ligand 
GtoPdb Ligand ID: 7930
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Abbreviated name: ELA
Synonyms: ELABELA | Ende | tdl | toddler
Compound class:
Endogenous peptide in human, mouse or rat
Comment: ELA signals via the apelin receptor to mediate endoderm differentiation and embryonic heart morphogenesis, and is present prior to the expression of apelin, making this the earliest ligand recognised by the apelin receptor [1]. More recently (Apr 2017) the activity as an endogenous agonist of the Apelin APJ receptor in the adult cardiovascular system was demonstracted [3].
Species: Human
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Related Sequences  |
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| apelin receptor early endogenous ligand {Sp: Mouse} |
Targetsapelin receptor |
| Elabela/Toddler-32 {Sp: Human} |
Targetsapelin receptor |
| Elabela/Toddler-21 {Sp: Human} |
Targetsapelin receptor |
| Elabela/Toddler-11 {Sp: Human} |
Targetsapelin receptor |
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