Cl-   Click here for help

GtoPdb Ligand ID: 2339

Synonyms: chloride
Compound class: Inorganic
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
References
1. Bhattacharjee A, Joiner WJ, Wu M, Yang Y, Sigworth FJ, Kaczmarek LK. (2003)
Slick (Slo2.1), a rapidly-gating sodium-activated potassium channel inhibited by ATP.
J Neurosci, 23 (37): 11681-91. [PMID:14684870]
2. Iharada M, Miyaji T, Fujimoto T, Hiasa M, Anzai N, Omote H, Moriyama Y. (2010)
Type 1 sodium-dependent phosphate transporter (SLC17A1 Protein) is a Cl(-)-dependent urate exporter.
J Biol Chem, 285 (34): 26107-13. [PMID:20566650]
3. Mistrík P, Daudet N, Morandell K, Ashmore JF. (2012)
Mammalian prestin is a weak Cl⁻/HCO₃⁻ electrogenic antiporter.
J Physiol (Lond.), 590 (Pt 22): 5597-610. [PMID:22890707]
4. Yuan A, Santi CM, Wei A, Wang ZW, Pollak K, Nonet M, Kaczmarek L, Crowder CM, Salkoff L. (2003)
The sodium-activated potassium channel is encoded by a member of the Slo gene family.
Neuron, 37 (5): 765-73. [PMID:12628167]