Synonyms: LM 427 | Mycobutin® | Rifabutine
rifabutin is an approved drug (FDA (1992), UK (2003))
Compound class:
Synthetic organic
Comment: Rifabutin is a derivative of rifamycin S and belongs to the ansamycin group of antibacterial compounds [1]. It is on the World Health Organization's Model List of Essential Medicines (link provided in the Classification table, under the Summary tab below) for use as an oral antituberculosis medication.
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No information available. |
Summary of Clinical Use |
Rifabutin can be used as a monotherapy to treat latent tuberculosis, or in combination with other antimycobacterial medications for active infection. It is most commonly used in people with HIV/AIDS who are taking antiretroviral drugs and who are unable to be prescribed rifampicin. |
External links |
For extended ADME data see the following: Electronic Medicines Compendium (eMC) Drugs.com |