L-365260

Ligand id: 879

Name: L-365260

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 73.8
Molecular weight 398.17
XLogP 4.22
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
CCK2 receptor Hs Antagonist Antagonist 8.4 pIC50 - 2
pIC50 8.4 (IC50 3.98x10-9 M) [2]
CCK1 receptor Rn Antagonist Antagonist 6.6 pIC50 - 1
pIC50 6.6 [1]