CCK-8

Ligand id: 864

Name: CCK-8

Species: Human, Mouse, Rat

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: cck-8, cholecystokinin

Structure and Physico-chemical Properties

2D Structure
Click here for structure editor

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Natural/Endogenous Targets
Target
CCK1 receptor
CCK2 receptor
Transporters Moving this Compound Across a Lipid Membrane
Transporter EC number Reaction Reference
OATP1B3
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CCK2 receptor Hs Agonist Full agonist 9.9 – 10.0 pIC50 - 3-4
pIC50 9.9 – 10.0 [3-4]
CCK1 receptor Rn Agonist Full agonist 7.2 – 9.9 pIC50 - 2
pIC50 9.9 [2]
pIC50 7.2 [2]
CCK1 receptor Hs Agonist Agonist - - -
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Targets where the ligand is described in the comment field
Target Comment
Ligand mentioned in the following text fields