CXCL122 (dimer)   Click here for help

GtoPdb Ligand ID: 8535

Comment: A constitutive dimer of human CXCL12α carrying two cysteine substitutions (L36C and A65C) promoting the formation of trans-peptide disulphide bonds which lock the dimer structure [2].
Click here for help
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CXCR4 Hs Agonist Partial agonist <6.0 pKd - 1
pKd <6.0 (Kd >1x10-6 M) [1]