α-scorpion toxin 2   Click here for help

GtoPdb Ligand ID: 2618

Synonyms: α-mammal toxin Lqh2 | Lqh II | LqhII | LqTx-2
Comment: Toxin from Leiurus quinquestriatus hebraeus (Yellow scorpion).
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Selectivity at ion channels
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Nav1.2 Rn Gating inhibitor Slows inactivation 8.7 pKd - 2
pKd 8.7 Inhibitor of fast activation [2]
Voltage: Physiological
Nav1.5 Rn Gating inhibitor Slows inactivation 7.7 pKd - 2
pKd 7.7 Inhibitor of fast activation [2]
Voltage: Physiological
Nav1.2 Rn Gating inhibitor Slows inactivation 9.1 pEC50 - 1
pEC50 9.1 Inhibitor of fast activation [1]
Voltage: -120.0 mV