ErgTx-1   Click here for help

GtoPdb Ligand ID: 2612

Synonyms: CnErg1 | CnErgTx1 | ergtoxin | ergtoxin-like protein 1 | ErgTx | ErgTx1 | potassium channel toxin gamma-KTx 1.1
Comment: From the venom of Centruroides noxius (Mexican scorpion)
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Selectivity at ion channels
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Kv11.2 Rn Gating inhibitor - 8.5 pKd - 3
pKd 8.5 [3]
Kv11.3 Rn Channel blocker Pore blocker 8.4 pKd - 4
pKd 8.4 [4]
Kv11.1 Hs Channel blocker - 8.3 pKd - 2
pKd 8.3 [2]
Voltage: -70.0 mV
Kv11.1 Rn Channel blocker - 8.2 pKd - 2
pKd 8.2 [2]
Voltage: -70.0 mV
Kv11.2 Hs Gating inhibitor Inhibition 6.7 pKd - 1
pKd 6.7 [1]