Lei-Dab7   Click here for help

GtoPdb Ligand ID: 2315

Comment: Synthetic analogue of leiurotoxin I
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Selectivity at ion channels
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
KCa2.3 Hs Channel blocker Antagonist 8.4 pKd - 1
pKd 8.4 (Kd 3.8x10-9 M) [1]
KCa2.2 Hs Channel blocker Antagonist 8.3 pIC50 - 1
pIC50 8.3 [1]
KCa2.1 Hs Channel blocker Antagonist 5.2 pIC50 - 1
pIC50 5.2 (IC50 6x10-6 M) [1]
Voltage: -120.0 – 40.0 mV