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AMG3054   Click here for help

GtoPdb Ligand ID: 9587

Compound class: Peptide
Comment: Apelin mimetic peptide agonist with reduced conformational flexibility, adopts a lactam constrained curved structure [1].
Peptide Sequence Click here for help
KFRRQRPXXQHKKXXPX
Lys-Phe-Arg-Arg-Gln-Arg-Pro-hArg-Cha-Glu-His-Lys-Lys-Oic-Nle-Pro-4-Cl-Phe
Chemical Modification
hArg, Cha, Oic, Nle and 4-Cl-Phe are unnatural amino acid counterparts. There is a lactam ring between Glu8 and Lys13 [1].