ligelizumab   Click here for help

GtoPdb Ligand ID: 8997

Synonyms: CL-2C | NVP-QGE031 | QGE031
Immunopharmacology Ligand
Compound class: Antibody
Comment: Ligelizumab is a humanized, investigational high-affinity anti-IgE monoclonal antibody with anti-inflammatory potential [1], with improved pharmacokinetics and clinical effects compared to omalizumab.
Peptide sequences for this antibody are available from its IMGT/mAb-DB record.
BLAST peptide sequence analysis reveals identical matches with antibody sequences claimed in patent US7531169 B2, where it is the clone designated as CL-2C [3].
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
9653 ligelizumab
Synonyms Click here for help
CL-2C | NVP-QGE031 | QGE031
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 422
Other databases
GtoPdb PubChem SID 310264775
Search PubMed clinical trials ligelizumab
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