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Elabela/Toddler-11   Click here for help

GtoPdb Ligand ID: 8526

Abbreviated name: ELA-11
Compound class: Endogenous peptide in human, mouse or rat
Comment: Elabela/Toddler-11 is a predicted dibasic cleavage site isoform of apelin receptor early endogenous ligand
Species: Human
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Ligand Activity Visualisation Charts

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View interactive charts of activity data across species

Elabela/Toddler-11 is commercially available from our sponsors

2D Structure
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2D Structure

An image of the ligand's 2D structure. For small molecules with SMILES these are drawn using the NCI/CADD Chemical Identifier Resolver. Click on the image to access the chemical structure search tool with the ligand pre-loaded in the structure editor. For other types of ligands, e.g. longer nucleotides and peptides, a manually drawn representation of the molecule may be provided.

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SMILES / InChI / InChIKey
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SMILES / InChI / InChIKey

SMILES (Simplified Molecular Input Line Entry Specification) A specification for unambiguously describing the structure of chemical molecules using short ASCII strings. Canonical SMILES specify a unique representation of the 2D structure without chiral or isotopic specifications. Isomeric SMILES include chiral specification and isotopes.

Standard InChI (IUPAC International Chemical Identifier) and InChIKey InChI is a non-proprietary, standard, textual identifier for chemical substances designed to facilitate linking of information and database searching. An InChIKey is a simplified version of a full InChI, designed for easier web searching.

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)

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Canonical SMILES CSCCC(C(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1CCCC1C(=O)NC(C(=O)N1CCCC1C(=O)O)Cc1ccccc1)C(C)C)CCCN=C(N)N)CO)Cc1c[nH]cn1)CC(C)C)NC(=O)C(CS)N
Isomeric SMILES CSCC[C@H](NC(=O)[C@@H](N)CS)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)O)C(C)C
InChI InChI=1S/C58H90N16O13S2/c1-32(2)25-39(68-52(81)43-16-10-21-72(43)54(83)38(19-24-89-5)66-47(76)36(59)30-88)49(78)67-40(27-35-28-62-31-64-35)50(79)70-42(29-75)51(80)65-37(15-9-20-63-58(60)61)48(77)71-46(33(3)4)56(85)73-22-11-17-44(73)53(82)69-41(26-34-13-7-6-8-14-34)55(84)74-23-12-18-45(74)57(86)87/h6-8,13-14,28,31-33,36-46,75,88H,9-12,15-27,29-30,59H2,1-5H3,(H,62,64)(H,65,80)(H,66,76)(H,67,78)(H,68,81)(H,69,82)(H,70,79)(H,71,77)(H,86,87)(H4,60,61,63)/t36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-/m0/s1
InChI Key XXKPNJFJXZBRMX-HDKAIKTRSA-N

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
APELA apelin receptor early endogenous ligand Human prepro-apelin receptor early endogenous ligand -
Database Links Click here for help
Specialist databases
GPCRdb Ligand Elabela/Toddler-11
Other databases
Ensembl Gene ENSG00000248329 (Hs)
GtoPdb PubChem SID 252166728
Human Protein Atlas ENSG00000248329 (Hs)
PubChem CID 127043376
Search Google for chemical match using the InChIKey XXKPNJFJXZBRMX-HDKAIKTRSA-N
Search Google for chemicals with the same backbone XXKPNJFJXZBRMX
UniChem Compound Search for chemical match using the InChIKey XXKPNJFJXZBRMX-HDKAIKTRSA-N
UniChem Connectivity Search for chemical match using the InChIKey XXKPNJFJXZBRMX-HDKAIKTRSA-N
UniProtKB P0DMC3 (Hs)

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Product supplier links are provided as a service to assist in identifying commercial suppliers of reagents that are mentioned on the IUPHAR/BPS Guide to PHARMACOLOGY database website, and do not imply their endorsement by NC-IUPHAR.

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MedChemExpress
ELA-11(human) (links to external site)
Cat. No. HY-P2197