Classification
Compound class	Endogenous peptide in human, mouse or rat
Ligand families/groups	Chemokines

Synonyms

SDF-1β | stromal cell-derived factor-1 (SDF-1) | stromal cell-derived factor-1β

Comments

CXCL12-1α and β were the first isoforms of this chemokine identified. Both proteins contain a signal peptide sequence that medaites their secretion via the canonical intracellular secretory pathway. CXCL12 participates in a variety of processes central to homeostasis and physiology, exerting its biological effects by binding to the chemokine receptors CXCR4 and CXCR7.

Gene/Precursor

Gene symbol Gene name Species Precursor protein name Synonyms CXCL12 C-X-C motif chemokine ligand 12 Human chemokine (C-X-C motif) ligand 12 chemokine (C-X-C motif) ligand 12, PBSF, SCYB12, SDF1, SDF-1a, SDF1A, SDF-1b, SDF1B, stromal cell-derived factor 1, TLSF-a, TLSF-b, TPAR1

Database Links
Ensembl Gene	ENSG00000107562 (Hs)
GtoPdb PubChem SID	135651882
Human Protein Atlas	ENSG00000107562 (Hs)
OMIM	600835 (Hs)
RefSeq Protein	NP_000600 (Hs)
UniProtKB	P48061 (Hs)
Wikipedia	SDF-1_(biology) (Hs)