CXCL10   Click here for help

GtoPdb Ligand ID: 835

Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: CXCL10 is a C-X-C motif chemokine preferentially expressed by Th1 lymphocytes. It exerts its biological effects via interaction with the CXCR3 GPCR.
Species: Human
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Chemokines
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
CXCL10 C-X-C motif chemokine ligand 10 Human chemokine (C-X-C motif) ligand 10 C7, chemokine (C-X-C motif) ligand 10, crg-2, gIP-10, IFI10, INP10, IP-10, mob-1, SCYB10, small inducible cytokine subfamily B (Cys-X-Cys), member 10
Database Links Click here for help
Specialist databases
GPCRdb Ligand CXCL10
Other databases
Ensembl Gene ENSG00000169245 (Hs)
GtoPdb PubChem SID 135651705
Human Protein Atlas ENSG00000169245 (Hs)
OMIM 147310 (Hs)
RefSeq Protein NP_001556 (Hs)
UniProtKB P02778 (Hs)
Wikipedia CXCL10 (Hs)