AZD7325   Click here for help

GtoPdb Ligand ID: 7712

Synonyms: AZD 7325 | AZD-7325
Compound class: Synthetic organic
Comment: AZD7325 was developed as a positive allosteric modulator of the GABAA α2 and α3 channels and was investigated as a treatment for generalised anxiety disorder. This compound is now included in AstaZeneca's Open Innovation Pharmacology Toolbox.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 90.13
Molecular weight 354.15
XLogP 3.2
No. Lipinski's rules broken 0
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Canonical SMILES CCCNC(=O)c1nnc2c(c1N)cccc2c1c(F)cccc1OC
Isomeric SMILES CCCNC(=O)c1nnc2c(c1N)cccc2c1c(F)cccc1OC
InChI InChI=1S/C19H19FN4O2/c1-3-10-22-19(25)18-16(21)12-7-4-6-11(17(12)23-24-18)15-13(20)8-5-9-14(15)26-2/h4-9H,3,10H2,1-2H3,(H2,21,23)(H,22,25)
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
Synonyms Click here for help
AZD 7325 | AZD-7325
Database Links Click here for help
Specialist databases
GPCRdb Ligand AZD7325
Other databases
ChEMBL Ligand CHEMBL1783282
GtoPdb PubChem SID 223366045
PubChem CID 23581869
Search Google for chemical match using the InChIKey KYDURMHFWXCKMW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone KYDURMHFWXCKMW
UniChem Compound Search for chemical match using the InChIKey KYDURMHFWXCKMW-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey KYDURMHFWXCKMW-UHFFFAOYSA-N