benralizumab   Click here for help

GtoPdb Ligand ID: 7674

Synonyms: BIW-8405 | Fasenra® | KHK4563 | MEDI-563
Approved drug Immunopharmacology Ligand
benralizumab is an approved drug (FDA (2017), EMA (2018))
Compound class: Antibody
Comment: Benralizumab is a humanized, afucosylated mAb targeting the IL5Rα which is expressed by cells of the eosinophil lineage. The antibody is afucosylated (ie has fucose containing oligosaccharide side-chains removed) to improve structure, stability, and biological function.
Peptide sequence information for this antibody is available from its IMGT/mAb-DB link.
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Classification Click here for help
Compound class Antibody
Approved drug? Yes (FDA (2017), EMA (2018))
International Nonproprietary Names Click here for help
INN number INN
9233 benralizumab
Synonyms Click here for help
BIW-8405 | Fasenra® | KHK4563 | MEDI-563
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 334
Other databases
ChEMBL Ligand CHEMBL1742991
GtoPdb PubChem SID 223366009
Search PubMed clinical trials benralizumab
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Search PubMed titles/abstracts benralizumab
Wikipedia Benralizumab