crofelemer   Click here for help

GtoPdb Ligand ID: 7453

Synonyms: Fulyzaq® | SP-303
Approved drug
crofelemer is an approved drug (FDA (2012))
Compound class: Natural product or derivative
Comment: Crofelemer is an oligomeric proanthocyanidin extracted from Croton lechleri, a South American flowering tree of the Euphorbiaceae (or spurges). We do not show a chemical structure for this complex molecule, but [2] shows a putative chemical structure.
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species

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View more information in the IUPHAR Pharmacology Education Project: crofelemer

Classification Click here for help
Compound class Natural product or derivative
Approved drug? Yes (FDA (2012))
Synonyms Click here for help
Fulyzaq® | SP-303
Database Links Click here for help
ChEMBL Ligand CHEMBL2108184
DrugBank Ligand DB04941
GtoPdb PubChem SID 187051756
Wikipedia Crofelemer