eszopiclone   Click here for help

GtoPdb Ligand ID: 7429

Synonyms: (S)-zopiclone | Lunesta®
Approved drug
eszopiclone is an approved drug (FDA (2004))
Compound class: Synthetic organic
Comment: This drug is the S enantiomer of zopiclone.
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 9
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 91.76
Molecular weight 388.11
XLogP 0.29
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES CN1CCN(CC1)C(=O)OC1c2nccnc2C(=O)N1c1ccc(cn1)Cl
Isomeric SMILES CN1CCN(CC1)C(=O)O[C@H]1c2nccnc2C(=O)N1c1ccc(cn1)Cl
InChI InChI=1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3/t16-/m0/s1
InChI Key GBBSUAFBMRNDJC-INIZCTEOSA-N
Classification Click here for help
Compound class Synthetic organic
Ligand families/groups Benzodiazepine class drugs
Approved drug? Yes (FDA (2004))
IUPAC Name Click here for help
[(7S)-6-(5-chloropyridin-2-yl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate
International Nonproprietary Names Click here for help
INN number INN
8258 eszopiclone
Synonyms Click here for help
(S)-zopiclone | Lunesta®
Database Links Click here for help
CAS Registry No. 138729-47-2
ChEMBL Ligand CHEMBL1522
DrugBank Ligand DB00402
DrugCentral Ligand 1068
GtoPdb PubChem SID 178104001
PubChem CID 969472
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UniChem Compound Search for chemical match using the InChIKey GBBSUAFBMRNDJC-INIZCTEOSA-N
UniChem Connectivity Search for chemical match using the InChIKey GBBSUAFBMRNDJC-INIZCTEOSA-N
Wikipedia Eszopiclone