- Guide to PHARMACOLOGY
Molecular properties generated using the CDK
|Compound class||Synthetic organic|
|Ligand families/groups||Antimalarial ligands|
|Approved drug?||Yes (FDA (1967), UK (2000))|
|WHO Essential Medicine||WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.|
|International Nonproprietary Names|
|BMY-28689 | Monodox® | Vibramycin®|
|Doxycycline is a tetracycline based antibiotic. It has been repurposed as a low-potency human metalloprotease inhibitor for periodontitis and is also used as an antimalarial therapy.
There are a number of salt forms in PubChem. The chemical structure we show here matches that of the consensus structure in PubChem, listed in the links table below. The DrugBank, ChEBI and ChEMBL entries for doxycycline show a different structure.
Doxycycline is one of the key access group antibacterials on the World Health Organisation's List of Essential Medicines. Click here to access the pdf version of the WHO's 21st Essential Medicines list (2019).
The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY.
|CAS Registry No.||564-25-0 (source: PubChem)|
|GtoPdb PubChem SID||178103078|
|Search Google for chemical match using the InChIKey||SGKRLCUYIXIAHR-AKNGSSGZSA-N|
|Search Google for chemicals with the same backbone||SGKRLCUYIXIAHR|
|Search PubMed clinical trials||doxycycline|
|Search PubMed titles||doxycycline|
|Search PubMed titles/abstracts||doxycycline|
|Search UniChem for chemical match using the InChIKey||SGKRLCUYIXIAHR-AKNGSSGZSA-N|
|Search UniChem for chemicals with the same backbone||SGKRLCUYIXIAHR|