- Guide to PHARMACOLOGY
Synonyms: AC1O5VPR | ASN 11124542
Compound class: Synthetic organic
Comment: This is compound 16 in  which has been shown to be an ATP competitive inhibitor blocking autophosphorylation of PKR.
Double-stranded RNA-activated protein kinase (PKR) is also known as eukaryotic initiation factor 2 subunit α (eIF2α).
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|Compound class||Synthetic organic|
|AC1O5VPR | ASN 11124542|
|CAS Registry No.||608512-97-6|
|GtoPdb PubChem SID||178102648|
|RCSB PDB Ligand||34L|
|Search Google for chemical match using the InChIKey||VFBGXTUGODTSPK-BAQGIRSFSA-N|
|Search Google for chemicals with the same backbone||VFBGXTUGODTSPK|
|UniChem Compound Search for chemical match using the InChIKey||VFBGXTUGODTSPK-BAQGIRSFSA-N|
|UniChem Connectivity Search for chemical match using the InChIKey||VFBGXTUGODTSPK-BAQGIRSFSA-N|
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Cat. No. 5382