sumatriptan   Click here for help

GtoPdb Ligand ID: 54

Synonyms: GR-43175C | Imigran® | Tosymra® (nasal spray)
Approved drug
sumatriptan is an approved drug (FDA (1992))
Compound class: Synthetic organic
Comment: Sumatriptan is a selective serotonin 5-HT1B/ID receptor agonist.
Marketed formulations contain sumatriptan succinate (PubChem CID 59772).
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 73.58
Molecular weight 295.14
XLogP 0.88
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES CNS(=O)(=O)Cc1ccc2c(c1)c(CCN(C)C)c[nH]2
Isomeric SMILES CNS(=O)(=O)Cc1ccc2c(c1)c(CCN(C)C)c[nH]2
InChI InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3
InChI Key KQKPFRSPSRPDEB-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1992))
WHO Essential Medicine WHO Essential Medicines List (EML) (22nd List, 2021). Access PDF version.
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IUPAC Name Click here for help
1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methylmethanesulfonamide
International Nonproprietary Names Click here for help
INN number INN
6125 sumatriptan
Synonyms Click here for help
GR-43175C | Imigran® | Tosymra® (nasal spray)
Database Links Click here for help
CAS Registry No. 103628-46-2
ChEBI CHEBI:10650
ChEMBL Ligand CHEMBL128
DrugBank Ligand DB00669
DrugCentral Ligand 2543
GtoPdb PubChem SID 135651095
PubChem CID 5358
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UniChem Compound Search for chemical match using the InChIKey KQKPFRSPSRPDEB-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey KQKPFRSPSRPDEB-UHFFFAOYSA-N
Wikipedia Sumatriptan