TL6   Click here for help

GtoPdb Ligand ID: 5072

Synonyms: activation-inducible TNF-related ligand | glucocorticoid- induced TNF-related ligand
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: TL6 (official name, tumor necrosis factor ligand superfamily member 18) is a cytokine belonging to the tumor necrosis factor (TNF) ligand family. It is thought to be involved in T cell interactions with endothelial cells, via binding to its receptor TNFRSF18 (a.k.a. AITR and GITR).
Species: Human
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Tumor necrosis factor superfamily ligands
Synonyms Click here for help
activation-inducible TNF-related ligand | glucocorticoid- induced TNF-related ligand
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
TNFSF18 TNF superfamily member 18 Human prepro-tumor necrosis factor ligand superfamily member 18 AITRL, hGITRL, TL6, tumor necrosis factor (ligand) superfamily, member 18, tumor necrosis factor superfamily member 18
Database Links Click here for help
CATH/Gene3D 2.60.120.40
Ensembl Gene ENSG00000120337 (Hs)
GtoPdb PubChem SID 178101765
Human Protein Atlas ENSG00000120337 (Hs)
UniProtKB Q9UNG2 (Hs)
Wikipedia TNFSF18