GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.

meso-DAP   Click here for help

GtoPdb Ligand ID: 5021

Synonyms: meso-diaminopimeilic acid
PDB Ligand
Compound class: Natural product
Comment: Diaminopimelic acid (DAP) is an amino acid, representing an epsilon-carboxy derivative of lysine. DAP is characteristic of cell walls of some bacteria.
2D Structure
Click here for help

2D Structure

An image of the ligand's 2D structure. For small molecules with SMILES these are drawn using the NCI/CADD Chemical Identifier Resolver. Click on the image to access the chemical structure search tool with the ligand pre-loaded in the structure editor. For other types of ligands, e.g. longer nucleotides and peptides, a manually drawn representation of the molecule may be provided.

✖
Click here for structure editor
Physico-chemical Properties
Click here for help

Physico-chemical Properties

Calculated molecular properties are available for small molecules and natural products (not peptides). Properties were generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/). All properties were selected to enable the prediction of the Lipinski Rule-of-Five profile or ‘druglikeness’ for each ligand. For more info on each category see the help pages.

✖
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 6
Topological polar surface area 126.64
Molecular weight 190.1
XLogP -3.46
No. Lipinski's rules broken 0

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)
SMILES / InChI / InChIKey
Click here for help

SMILES / InChI / InChIKey

SMILES (Simplified Molecular Input Line Entry Specification) A specification for unambiguously describing the structure of chemical molecules using short ASCII strings. Canonical SMILES specify a unique representation of the 2D structure without chiral or isotopic specifications. Isomeric SMILES include chiral specification and isotopes.

Standard InChI (IUPAC International Chemical Identifier) and InChIKey InChI is a non-proprietary, standard, textual identifier for chemical substances designed to facilitate linking of information and database searching. An InChIKey is a simplified version of a full InChI, designed for easier web searching.

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)

✖
Canonical SMILES NC(C(=O)O)CCCC(C(=O)O)N
Isomeric SMILES N[C@H](C(=O)O)CCC[C@H](C(=O)O)N
InChI InChI=1S/C7H14N2O4/c8-4(6(10)11)2-1-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)/t4-,5+
InChI Key GMKMEZVLHJARHF-SYDPRGILSA-N

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)
Classification Click here for help
Compound class Natural product
IUPAC Name Click here for help
(2R,6S)-2,6-diaminoheptanedioic acid
Synonyms Click here for help
meso-diaminopimeilic acid
Database Links Click here for help
CAS Registry No. 922-54-3 (source: Scifinder)
ChEBI CHEBI:16488
ChEMBL Ligand CHEMBL415306
GtoPdb PubChem SID 178101718
PubChem CID 99290
RCSB PDB Ligand API
Search Google for chemical match using the InChIKey GMKMEZVLHJARHF-SYDPRGILSA-N
Search Google for chemicals with the same backbone GMKMEZVLHJARHF
UniChem Compound Search for chemical match using the InChIKey GMKMEZVLHJARHF-SYDPRGILSA-N
UniChem Connectivity Search for chemical match using the InChIKey GMKMEZVLHJARHF-SYDPRGILSA-N
Wikipedia Diaminopimelic_acid