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IL-17A   Click here for help

GtoPdb Ligand ID: 4982

Synonyms: CTLA-8 | interleukin-17 alpha
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: Forms homodimeric ligand IL-17A, or heterodimeric IL-17A/IL-17F.
Species: Human
Is a component of
IL-17A/IL-17F
Peptide Sequence Click here for help
GITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINAD
GNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVA
Selected 3D Structures
PDB Id: 2VXS
Image of ligand 3D structure from RCSB PDB
Post-translational Modification
Predicted N-linked glycosylation of aspragine residue at position 45; predicted disulphide bond formation between cysteine residues at positions 71 and 121, and 76 and 123