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relaxin (A chain)   Click here for help

GtoPdb Ligand ID: 3746

Synonyms: H2 relaxin (A chain)
Compound class: Endogenous peptide in human, mouse or rat
Species: Human
Is a component of
relaxin
Peptide Sequence Click here for help
XLYSALANKCCHVGCTKRSLARFC
pGlu-Leu-Tyr-Ser-Ala-Leu-Ala-Asn-Lys-Cys-Cys-His-Val-Gly-Cys-Thr-Lys-Arg-Ser-Leu-Ala-Arg-Phe-Cys
Post-translational Modification
The N-terminal glutamine is cyclised into pyroglutamate (pGlu/X).

Fully active H2 relaxin is a heterodimer of the B chain and the A chain linked by two disulfide bonds, the first between B chain (residue 35) and A chain (residue 172), and the second between B chain (residue 47) and A chain (residue 185).