- Guide to PHARMACOLOGY
Synonyms: BA-679-BR | Spiriva®
tiotropium is an approved drug (FDA (2004))
Compound class: Synthetic organic
Comment: We have chosen to display the structure of the parent compound, tiotropium, as this reflects the compound used in the experimental data listed under the 'biological activity' tab, and the links in the table above also represent the parent compound. However, the INN-assigned compound is in complex with bromide, the approved drug is also administered in this preparation. Note that the activity data in PubChem for this compound is split between the parent and the preparation with bromide.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
View more information in the IUPHAR Pharmacology Education Project: tiotropium
|Compound class||Synthetic organic|
|Approved drug?||Yes (FDA (2004))|
|WHO Essential Medicine||WHO Essential Medicines List (EML) (22nd List, 2021). Access PDF version.
Click to view more information about the WHO Model Lists of Essential Medicines.
|International Nonproprietary Names|
|BA-679-BR | Spiriva®|
|CAS Registry No.||186691-13-4|
|GtoPdb PubChem SID||135651266|
|Search Google for chemical match using the InChIKey||LERNTVKEWCAPOY-FPISHFTHSA-N|
|Search Google for chemicals with the same backbone||LERNTVKEWCAPOY|
|Search PubMed clinical trials||tiotropium bromide|
|Search PubMed titles||tiotropium bromide|
|Search PubMed titles/abstracts||tiotropium bromide|
|SynPHARM||82388 (in complex with M1 receptor)|
|UniChem Compound Search for chemical match using the InChIKey||LERNTVKEWCAPOY-FPISHFTHSA-N|
|UniChem Connectivity Search for chemical match using the InChIKey||LERNTVKEWCAPOY-FPISHFTHSA-N|