- Guide to PHARMACOLOGY
Abbreviated name: RTX
Compound class: Natural product or derivative
Comment: Resiniferatoxin, an extract from resin spurge (Euphorbia resinifera), is a TRPV1 agonist.
There is some ambiguity online and in the literature as to the exact stereochemistry of resiniferatoxin. The representation shown here matches that in the PubChem and ChEMBL links above, while several tautomers and stereoisomers are also listed on PubChem, and ChEBI represents the compound with the entry CHEBI:8809.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|Compound class||Natural product or derivative|
|CAS Registry No.||57444-62-9 (source: Scifinder)|
|GtoPdb PubChem SID||53801085|
|RCSB PDB Ligand||6EU|
|Search Google for chemical match using the InChIKey||DSDNAKHZNJAGHN-MXTYGGKSSA-N|
|Search Google for chemicals with the same backbone||DSDNAKHZNJAGHN|
|UniChem Compound Search for chemical match using the InChIKey||DSDNAKHZNJAGHN-MXTYGGKSSA-N|
|UniChem Connectivity Search for chemical match using the InChIKey||DSDNAKHZNJAGHN-MXTYGGKSSA-N|