diazoxide   Click here for help

GtoPdb Ligand ID: 2409

Synonyms: Proglycem® | SCH-6783 | SRG-95213
Approved drug PDB Ligand
diazoxide is an approved drug (FDA (1973))
Compound class: Synthetic organic
Comment: Diazoxide is a potassium channel activator.
Click here for help
2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 66.91
Molecular weight 229.99
XLogP 1.94
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Click here for help
Canonical SMILES Clc1ccc2c(c1)S(=O)(=O)N=C(N2)C
Isomeric SMILES Clc1ccc2c(c1)S(=O)(=O)N=C(N2)C
InChI InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)
InChI Key GDLBFKVLRPITMI-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1973))
WHO Essential Medicine WHO Essential Medicines List (EML) (23rd List, 2023). Access PDF version.
Click to view more information about the WHO Model Lists of Essential Medicines.
IUPAC Name Click here for help
7-chloro-3-methyl-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide
International Nonproprietary Names Click here for help
INN number INN
1294 diazoxide
Synonyms Click here for help
Proglycem® | SCH-6783 | SRG-95213
Database Links Click here for help
BindingDB Ligand 50241108
CAS Registry No. 364-98-7
ChEBI CHEBI:4495
ChEMBL Ligand CHEMBL181
DrugBank Ligand DB01119
DrugCentral Ligand 854
GtoPdb PubChem SID 135650176
PubChem CID 3019
RCSB PDB Ligand 20J
Search Google for chemical match using the InChIKey GDLBFKVLRPITMI-UHFFFAOYSA-N
Search Google for chemicals with the same backbone GDLBFKVLRPITMI
Search PubMed clinical trials diazoxide
Search PubMed titles diazoxide
Search PubMed titles/abstracts diazoxide
UniChem Compound Search for chemical match using the InChIKey GDLBFKVLRPITMI-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey GDLBFKVLRPITMI-UHFFFAOYSA-N
Wikipedia Diazoxide

Product suppliers

View disclaimer

Tocris
Diazoxide (links to external site)
Cat. No. 0964