fluphenazine   Click here for help

GtoPdb Ligand ID: 204

Synonyms: Prolixin®
Approved drug
fluphenazine is an approved drug (FDA (1959))
Compound class: Synthetic organic
Comment: Fluphenazine belongs to the family of phenothiazine anti-psychotic drugs.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 55.25
Molecular weight 437.17
XLogP 4.16
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES OCCN1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(cc2)C(F)(F)F
Isomeric SMILES OCCN1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(cc2)C(F)(F)F
InChI InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2
InChI Key PLDUPXSUYLZYBN-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1959))
WHO Essential Medicine WHO Essential Medicines List (EML) (22nd List, 2021). Access PDF version.
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IUPAC Name Click here for help
2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol
International Nonproprietary Names Click here for help
INN number INN
946 fluphenazine
Synonyms Click here for help
Prolixin®
Database Links Click here for help
BindingDB Ligand 50017655
CAS Registry No. 69-23-8 (source: DrugBank)
ChEBI CHEBI:136842
ChEMBL Ligand CHEMBL726
DrugBank Ligand DB00623
DrugCentral Ligand 1212
GtoPdb PubChem SID 135650275
PubChem CID 3372
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Wikipedia Fluphenazine