- Guide to PHARMACOLOGY
Synonyms: Arthrotec® | BRN 4155643 | CCRIS 6859 | Cytotec® | HSDB 3573 | SC 29333
misoprostol (methyl ester) is an approved drug (FDA (1988))
Compound class: Synthetic organic
Comment: The INN-assigned approved drug misoprostol is a racemic mixture of two epimers and their enantiomers. For more information, please see the ChEBI link above. Note that the INN-assigned structure represents the methyl ester form of the compound as which the drug is administered. The drug is then converted in vivo to the active metabolite misoprostol (free acid form).
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
View more information in the IUPHAR Pharmacology Education Project: misoprostol
|Compound class||Synthetic organic|
|Approved drug?||Yes (FDA (1988))|
|WHO Essential Medicine||WHO Essential Medicines List (EML) (22nd List, 2021). Access PDF version.
Click to view more information about the WHO Model Lists of Essential Medicines.
|Active form||misoprostol (free acid form)|
|International Nonproprietary Names|
|Arthrotec® | BRN 4155643 | CCRIS 6859 | Cytotec® | HSDB 3573 | SC 29333|
|CAS Registry No.||59122-46-2 (source: Scifinder)|
|GtoPdb PubChem SID||135650611|
|Search Google for chemical match using the InChIKey||OJLOPKGSLYJEMD-URPKTTJQSA-N|
|Search Google for chemicals with the same backbone||OJLOPKGSLYJEMD|
|Search PubMed clinical trials||misoprostol|
|Search PubMed titles||misoprostol|
|Search PubMed titles/abstracts||misoprostol|
|UniChem Compound Search for chemical match using the InChIKey||OJLOPKGSLYJEMD-URPKTTJQSA-N|
|UniChem Connectivity Search for chemical match using the InChIKey||OJLOPKGSLYJEMD-URPKTTJQSA-N|
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Misoprostol (links to external site)
Cat. No. 2297