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peptide YY   Click here for help

GtoPdb Ligand ID: 1514

Abbreviated name: PYY
Synonyms: peptide tyrosine tyrosine
Compound class: Endogenous peptide in human, mouse or rat
Comment: Peptide YY is a neuropeptide Y2 receptor agonist. It has been investigated as a potential appetite suppressant [2,6,8-9].
Species: Human
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: peptide yy

Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
Synonyms Click here for help
peptide tyrosine tyrosine
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
PYY peptide YY Human prepro-PYY PYY1
Database Links Click here for help
Specialist databases
GPCRdb Ligand peptide YY
Other databases
CAS Registry No. 118997-30-1 (Hs)
Ensembl Gene ENSG00000131096 (Hs)
GtoPdb PubChem SID 135651873
Human Protein Atlas ENSG00000131096 (Hs)
UniProtKB P10082 (Hs)
Wikipedia Peptide_YY