GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.

perenostobart   Click here for help

GtoPdb Ligand ID: 12103

Synonyms: SRF-617 | SRF617
Immunopharmacology Ligand
Compound class: Antibody
Comment: Perenostobart is a monoclonal antibody that targets ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1/CD39). Based on analysis using the amino acid (aa) sequences provided in the INN documentation and patented aa sequences (via NCBI Blast: protein), perenostobart would appear to map to Surface Oncology's clinical lead anti-CD39 mAb SRF617. Surface Oncology claim anti-CD39 mAbs in patent US10738128B2 [1]. SRF617 is a fully human mAb that was designed to inhibit the enzymatic activity of ENTPD1/CD39.
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
12269 perenostobart
Synonyms Click here for help
SRF-617 | SRF617
Database Links Click here for help
CAS Registry No. 2643331-31-9 (source: WHO INN record)
GtoPdb PubChem SID 472319225
Search PubMed clinical trials perenostobart
Search PubMed titles perenostobart
Search PubMed titles/abstracts perenostobart