- Guide to PHARMACOLOGY
Synonyms: AEVI-002 | AVTX-002 | CERC-002 | MDGN-002 | SAR-252067 | SAR252067 
Compound class: Antibody
Comment: Quisovalimab (AVTX-002) is a clinical stage, fully human IgG4 anti-LIGHT (TNFSF14) monoclonal antibody. It was developed for anti-inflammatory potential . Quisovalimab binds to LIGHT and prevents it from interacting with its receptors on T cells .
As CERC-002, this agent was assessed for efficacy as a treament for COVID-19-related pneumonia and ARDS/acute lung injury, based on evidence of a pro-inflammatory effect of LIGHT on the interaction between T cells and airway smooth muscle cells .
|International Nonproprietary Names|
|AEVI-002 | AVTX-002 | CERC-002 | MDGN-002 | SAR-252067 | SAR252067 |
|GtoPdb PubChem SID||458923809|
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