leuprolide   Click here for help

GtoPdb Ligand ID: 1175

Synonyms: ABBOTT-43818 | Camcevi® | Fensolvi® (leuprolide acetate injectable suspension) | Lupron® | TAP-144
Approved drug
leuprolide is an approved drug (FDA (1985))
Compound class: Peptide
Comment: The marketed formulation contains leuprolide acetate.
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2D Structure
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SMILES / InChI / InChIKey
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Canonical SMILES CCNC(=O)C1CCCN1C(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(Cc1ccc(cc1)O)NC(=O)C(NC(=O)C(Cc1c[nH]c2c1cccc2)NC(=O)C(Cc1cnc[nH]1)NC(=O)C1CCC(=O)N1)CO)CC(C)C)CC(C)C)CCCN=C(N)N
Isomeric SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccc(cc1)O)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1)CO)CC(C)C)CC(C)C)CCCN=C(N)N
InChI InChI=1S/C59H84N16O12/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64)/t40-,41-,42-,43+,44-,45-,46-,47-,48-/m0/s1
InChI Key GFIJNRVAKGFPGQ-LIJARHBVSA-N
Classification Click here for help
Compound class Peptide
Approved drug? Yes (FDA (1985))
WHO Essential Medicine WHO Essential Medicines List (EML) (23rd List, 2023). Access PDF version.
Click to view more information about the WHO Model Lists of Essential Medicines.
International Nonproprietary Names Click here for help
INN number INN
5025 leuprorelin
Synonyms Click here for help
ABBOTT-43818 | Camcevi® | Fensolvi® (leuprolide acetate injectable suspension) | Lupron® | TAP-144
Database Links Click here for help
Specialist databases
GPCRdb Ligand leuprolide
Other databases
CAS Registry No. 53714-56-0
ChEMBL Ligand CHEMBL1201199
DrugBank Ligand DB00007
DrugCentral Ligand 1559
GtoPdb PubChem SID 135652260
PubChem CID 657181
Search Google for chemical match using the InChIKey GFIJNRVAKGFPGQ-LIJARHBVSA-N
Search Google for chemicals with the same backbone GFIJNRVAKGFPGQ
Search PubMed clinical trials leuprorelin
Search PubMed titles leuprorelin
Search PubMed titles/abstracts leuprorelin
UniChem Compound Search for chemical match using the InChIKey GFIJNRVAKGFPGQ-LIJARHBVSA-N
UniChem Connectivity Search for chemical match using the InChIKey GFIJNRVAKGFPGQ-LIJARHBVSA-N
Wikipedia Leuprorelin