GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.

FSH   Click here for help

GtoPdb Ligand ID: 1157

Synonyms: follitropin | human follicle stimulating hormone
Approved drug
FSH is an approved drug (FDA (1997))
Compound class: Endogenous peptide in human, mouse or rat
Comment: FSH is a 35.5 kDa glycoprotein heterodimer, consisting of an alpha (CGA) and a beta polypeptide (FSHB) subunit. This entry also represents urofollitropin, which is a purified form of FSH that is extracted from human menopausal urine.
Species: Human
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: fsh

Natural/Endogenous Targets
Target
FSH receptor
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
FSH receptor Primary target of this compound Ligand is endogenous in the given species Hs Agonist Agonist - - -
⤷
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Potency order of endogenous ligands at FSH receptor FSH (CGA, FSHB, P01215, P01225)
Ligand mentioned in the following text fields
Glycoprotein hormone receptors overview