ChEMBL ligand: CHEMBL278623 (AEZS-130, Ard-07, ARD-07, ARD07, EP-01572, EP01572, EP-1572, EP1572, JMV 1843, JMV-1843, Macimorelin, Macimorelina, Macimoreline, Macrilen, Solorel)
ghrelin receptor/Ghrelin receptor in Human [ChEMBL: CHEMBL4616] [GtoPdb: 246] [UniProtKB: Q92847] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
ghrelin receptor/Ghrelin receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4616] [GtoPdb: 246] [UniProtKB: Q92847]
ChEMBL	Binding affinity towards cloned human Growth hormone secretagogue receptor type I in LLC PK-1 cells using [125I][His9]-ghrelin as radioligand	B	6.91	pIC50	123	nM	IC50	J Med Chem (2003) 46: 1191-1203 [PMID:12646029]
ChEMBL	Binding affinity towards human pituitary Growth hormone secretagogue receptor using [125I][Tyr4]-ghrelin as radioligand	B	7.64	pIC50	22.9	nM	IC50	J Med Chem (2003) 46: 1191-1203 [PMID:12646029]
GtoPdb	In a radioligand displacement assay using 125I-labeled ghrelin as the probe, and human pituitary gland samples.	-	7.81	pIC50	15.6	nM	IC50	J Endocrinol Invest (2002) 25: RC26-8 [PMID:12240910]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]